{"id":14514,"date":"2025-04-30T15:28:51","date_gmt":"2025-04-30T14:28:51","guid":{"rendered":"https:\/\/youngentrepreneursinscience.com\/2025\/05\/21\/another-founding-failing-and-forging-ahead\/"},"modified":"2025-06-19T09:51:51","modified_gmt":"2025-06-19T08:51:51","slug":"where-molecules-meet-markets","status":"publish","type":"post","link":"https:\/\/youngentrepreneursinscience.com\/de\/2025\/04\/30\/where-molecules-meet-markets\/","title":{"rendered":"Where Molecules Meet Markets"},"content":{"rendered":"\n<p class=\"has-text-color has-link-color has-large-font-size wp-elements-b058de2acad618bede01724d94664cc3 wp-block-paragraph\" style=\"color:#f42222\">The Entrepreneurial Journey of Dr. Merle Fuchs<\/p>\n\n\n<div id=\"YES-BlogText-1\" class=\"YES-BlogText col-12\">\n\n  <div class=\"row\">\n        <div class=\"col-12 col-lg-2\">\n      <span class=\"posted-on\">Ver\u00f6ffentlicht am <br><strong><time class=\"entry-date published updated\" datetime=\"2025-04-30T15:28:51+01:00\">30 April, 2025<\/time><\/strong><\/span><br><br><span class=\"posted-by\"> Written by<br><strong><span class=\"author vcard\">Bianca Cramer<\/span><\/strong><\/span>    <\/div>\n    \n    <div\n      class=\"col-12 col-lg-8 \">\n      <p style=\"font-weight: 400\">Dr. Merle Fuchs has worn many hats in her career: scientist, advisor, founder, board member, and keynote speaker. But the thread that runs through her work is clear: a passion for turning complex scientific discoveries into tangible, practical innovations. We sat down with her to talk about her journey from the research lab to the entrepreneurial stage, the founding story of PRAMOMOLECULAR, and why entrepreneurial thinking is essential in every professional path.<\/p>\n<p>&nbsp;<\/p>\n    <\/div>\n\n      <\/div>\n\n<\/div>\n\n<div id=\"YES-BlogText-2\" class=\"YES-BlogText col-12\">\n\n  <div class=\"row\">\n    \n    <div\n      class=\"col-12 col-lg-8  offset-lg-2 \">\n      <h6 style=\"font-weight: 400\"><strong>Your background spans top universities and research institutes across Europe and the US. How did you transition from science into the world of business?<\/strong><\/h6>\n<p style=\"font-weight: 400\">I studied micro- and molecular biology at several institutions, including G\u00f6ttingen, T\u00fcbingen, Wageningen, and the Scripps Research Institute in California. My diploma and doctoral theses in evolutive protein design were carried out under Manfred Eigen at the Max Planck Institute in G\u00f6ttingen.<\/p>\n<p>I loved research deeply\u2014especially the freedom of working on my projects\u2014but I\u2019ve always been drawn to the application side of science. Coming from an entrepreneurial family, that mindset was with me early on. So, when the opportunity arose to receive international training in technology transfer as part of the BioRegio initiative in the 1990s, I took it. That became the turning point.<\/p>\n<p>Since then, I\u2019ve advised over 550 technology-oriented start-ups through my consulting company, TechnologieContor, and co-founded eight companies. For me, high-tech start-ups are the most direct way to turn knowledge into societal value. My focus has always been on innovation strategy, international market access, and financing, especially in biotech, chemistry, and photonics. Working closely with start-ups at different growth stages has taught me how to navigate both scientific and entrepreneurial uncertainty.<\/p>\n    <\/div>\n\n      <\/div>\n\n<\/div>\n\n<div id=\"YES-BlogCite-3\" class=\"YES-BlogCite col-12\">\n  <div class=\"row\">\n    <div class=\"col-12 col-lg-8 offset-lg-2 text-center\">\n            <div class=\"quote\">Most happens where different challenges, thought structures, and technologies collide and where there is an intensive exchange.<\/div>\n                <\/div>\n  <\/div>\n<\/div>\n\n<div id=\"YES-BlogText-4\" class=\"YES-BlogText col-12\">\n\n  <div class=\"row\">\n    \n    <div\n      class=\"col-12 col-lg-8  offset-lg-2 \">\n      <h6 style=\"font-weight: 400\"><strong>Was there a key insight or challenge that sparked the idea for PRAMOMOLECULAR?<\/strong><\/h6>\n<p style=\"font-weight: 400\">Yes. It began through a company I was involved in as a side investor\u2014BianoGMP. They produce therapeutic oligonucleotides like siRNAs in compliance with pharmaceutical standards. But what we kept running into was the issue of delivery. Small interfering RNAs are incredibly powerful tools, but getting them to the right place in the body, especially outside the liver, is extremely difficult.<\/p>\n<p style=\"font-weight: 400\">That\u2019s where PRAMOMOLECULAR comes in. We developed a platform that can deliver siRNA-based therapies to extrahepatic tissues with much higher efficiency than conventional methods. That opens the door for treating diseases previously considered unreachable via gene silencing\u2014neurological diseases, certain cancers, and inflammatory conditions, for example.<\/p>\n<p style=\"font-weight: 400\">So we\u2019re not just developing drug candidates; we\u2019re solving one of the biggest bottlenecks in therapeutic RNA delivery. This is exactly where science and entrepreneurship meet: identifying a bottleneck no one has solved yet and building the tools to change that.<\/p>\n<h6 style=\"font-weight: 400\"><strong>You presented this work on the Falling Walls Venture stage. What was that experience like, and what did you take away from it?<\/strong><\/h6>\n<p style=\"font-weight: 400\">It was exciting\u2014and honestly, a bit surreal. I was the oldest person on stage, representing the youngest start-up in the healthcare category. That contrast made it all the more memorable. But more than that, it was the atmosphere that struck me: the energy, the openness, the shared drive among founders from vastly different fields and countries. It was one of those rare spaces where science, entrepreneurship, and curiosity genuinely meet.<\/p>\n<p style=\"font-weight: 400\">Still, many of us in the health tech space couldn\u2019t help but notice how few investors engaged with the healthcare pitches. It&#8217;s a recurring challenge in our field: groundbreaking science tends to come with long development timelines and complex narratives, which don\u2019t always fit into conventional funding expectations.<\/p>\n<p style=\"font-weight: 400\">Even so, the experience was invaluable. I had inspiring conversations with people like Prof. Andrea T\u00fcttenberg from ActiTrexx, who\u2019s bringing novel treatments to patients with severe autoimmune diseases, and Salma Tamman from Reme-D, whose diagnostic work spans three continents. Those kinds of exchanges\u2014frank, ambitious, and generous\u2014are a big part of what keeps me going.<\/p>\n    <\/div>\n\n      <\/div>\n\n<\/div>\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"341\" src=\"https:\/\/youngentrepreneursinscience.com\/wp-content\/uploads\/2025\/05\/Fuchs_Founders-Tip-1024x341.jpg\" alt=\"\" class=\"wp-image-14523\" srcset=\"https:\/\/youngentrepreneursinscience.com\/wp-content\/uploads\/2025\/05\/Fuchs_Founders-Tip-1024x341.jpg 1024w, https:\/\/youngentrepreneursinscience.com\/wp-content\/uploads\/2025\/05\/Fuchs_Founders-Tip-300x100.jpg 300w, https:\/\/youngentrepreneursinscience.com\/wp-content\/uploads\/2025\/05\/Fuchs_Founders-Tip-768x256.jpg 768w, https:\/\/youngentrepreneursinscience.com\/wp-content\/uploads\/2025\/05\/Fuchs_Founders-Tip-1536x512.jpg 1536w, https:\/\/youngentrepreneursinscience.com\/wp-content\/uploads\/2025\/05\/Fuchs_Founders-Tip-2048x682.jpg 2048w, https:\/\/youngentrepreneursinscience.com\/wp-content\/uploads\/2025\/05\/Fuchs_Founders-Tip-200x67.jpg 200w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div id=\"YES-BlogText-5\" class=\"YES-BlogText col-12\">\n\n  <div class=\"row\">\n    \n    <div\n      class=\"col-12 col-lg-8  offset-lg-2 \">\n      <h6 style=\"font-weight: 400\"><strong>Let\u2019s talk about mindset. The YES program promotes the relevance of entrepreneurial thinking for all career paths researchers can take. Has that mindset been relevant for you\u2014even beyond business?<\/strong><\/h6>\n<p style=\"font-weight: 400\">Absolutely. Entrepreneurial thinking isn\u2019t just about launching a company\u2014it\u2019s a way of approaching problems and navigating complexity. It means having a vision, recognizing needs, weighing risks and opportunities, and making the most of limited resources. Those skills are useful everywhere: in science, in leadership, even in everyday life.<\/p>\n    <\/div>\n\n      <\/div>\n\n<\/div>\n\n<div id=\"YES-BlogCite-6\" class=\"YES-BlogCite col-12\">\n  <div class=\"row\">\n    <div class=\"col-12 col-lg-8 offset-lg-2 text-center\">\n            <div class=\"quote\">Self-motivation and perseverance are essential \u2013 you need to stay committed, especially when the going gets tough.<\/div>\n                <\/div>\n  <\/div>\n<\/div>\n\n<div id=\"YES-BlogText-7\" class=\"YES-BlogText col-12\">\n\n  <div class=\"row\">\n    \n    <div\n      class=\"col-12 col-lg-8  offset-lg-2 \">\n      <p style=\"font-weight: 400\">For me, one of the most important elements is self-leadership. Being able to reflect, adapt, make decisions, and communicate clearly\u2014especially in uncertain or high-pressure situations\u2014that\u2019s what truly defines an entrepreneurial mindset.<\/p>\n<h6 style=\"font-weight: 400\"><strong>What advice would you give to scientists who are thinking about entrepreneurship or founding a start-up?<\/strong><\/h6>\n<p style=\"font-weight: 400\">Start by attending pitch events early as an audience member and as a pitcher. At first, watch and listen. Later, present your idea. The act of turning your entire business model into a three- to ten-minute pitch forces clarity. You need to know what matters most. And yes, even if it feels outdated, I recommend writing a full 30-page business plan. It makes you think the whole company through\u2014from market to financing to regulation\u2014and prepares you for real conversations with partners and investors.<\/p>\n<p style=\"font-weight: 400\">Also, talk to other founders, especially those a little ahead of you. Learn from their mistakes and their wins. And make sure you don\u2019t build your plan in isolation\u2014discuss it, challenge it, revise it.<\/p>\n<h6 style=\"font-weight: 400\"><strong>How important is your network today\u2014and how do you keep it active?<\/strong><\/h6>\n<p style=\"font-weight: 400\">I started building my network during my studies, and over time it has become one of my most important assets. But networks aren\u2019t static\u2014you lose contacts, interests shift, and new technologies emerge. I make a point of staying active, meeting people at events, joining panels, and staying curious about other perspectives.<\/p>\n<p style=\"font-weight: 400\">That said, I do feel that in some places, there\u2019s more buzz than depth. At some start-up events, for example, you meet more consultants than founders. And still, as a society, we\u2019re not valuing technology and science-driven innovation as much as we should\u2014especially given the challenges we face in energy, climate, health, and food.<\/p>\n<h6 style=\"font-weight: 400\"><strong>What\u2019s your personal takeaway after all these years at the interface of science and entrepreneurship?<\/strong><\/h6>\n<p style=\"font-weight: 400\">Do excellent work\u2014and make sure people know about it. That means communicating clearly, reaching out, and building alliances. But above all, it means staying the course. Founding a company, especially in fields like biotech, isn\u2019t a sprint. It\u2019s a long-term commitment to solving hard problems\u2014and doing it with passion.<\/p>\n    <\/div>\n\n      <\/div>\n\n<\/div>\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div id=\"YES-BlogText-8\" class=\"YES-BlogText col-12\">\n\n  <div class=\"row\">\n    \n    <div\n      class=\"col-12 col-lg-8  offset-lg-2 \">\n      <h6>What happens next?<\/h6>\n<p>Check out our <a href=\"https:\/\/youngentrepreneursinscience.com\/events\/\" target=\"_blank\" rel=\"noopener\" data-auto-event-observed=\"true\">event calendar<span class=\"visually-hidden\">(\u00f6ffnet in einem neuen Fenster)<\/span><\/a> for upcoming workshops. Stay tuned for more updates, opportunities, and success stories!<\/p>\n<p>Connect with <a href=\"https:\/\/www.linkedin.com\/in\/merle-fuchs-05892511\/\">Merle<\/a> via LinkedIn!<\/p>\n<p><strong>Interviewer &amp; Editor, Design:<\/strong> Bianca Cramer<\/p>\n<p>&nbsp;<\/p>\n    <\/div>\n\n      <\/div>\n\n<\/div>\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Merle Fuchs has worn many hats in her career: scientist, advisor, founder, board member, and keynote speaker. But the thread that runs through her work is clear&#8230;<\/p>\n","protected":false},"author":91,"featured_media":14997,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[189],"tags":[1237,1280,1098],"class_list":["post-14514","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","tag-methods","tag-newsletter","tag-workshop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Where Molecules Meet Markets - YES<\/title>\n<meta name=\"description\" content=\"Sciencepreneur David explains his sciencepreneurship journey and what was the role of entrepreneurship workshop for scientists.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/youngentrepreneursinscience.com\/de\/2025\/04\/30\/where-molecules-meet-markets\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Where Molecules Meet Markets - 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